2006 US Open – Wheelchair women's singles
| Wheelchair women's singles | |
|---|---|
| 2006 US Open | |
| Champion |  Esther Vergeer |
| Runner-up | Sharon Walraven |
| Score | 6-1, 6-2 |
Defending champion Esther Vergeer defeated Yana Buchina in the final, 6–1, 6–2 to win the women's singles wheelchair tennis title at the 2006 US Open.
Draw
Key
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- ITF = ITF entry
- PR = Protected ranking
- SR = Special ranking
- SE = Special exempt
- JE = Junior exempt
- JR = Junior Accelerator Programme entrant
- CO = College Accelerator Programme entrant
- NG = Next Gen Accelerator Program entrant
- w/o = Walkover
- r = Retired
- d = Defaulted
Finals
| First round | Semifinals | Final | ||||||||||||||||||
| Esther Vergeer
| 6 | 6 | ||||||||||||||||||
 Kaitlyn Verfuerth
| 1 | 1 | ||||||||||||||||||
| Esther Vergeer
| 6 | 6 | ||||||||||||||||||
| Maaike Smit
| 1 | 2 | ||||||||||||||||||
| Beth Arnoult-Ritthaler
| 0 | 1 | ||||||||||||||||||
| Maaike Smit
| 6 | 6 | ||||||||||||||||||
| Esther Vergeer
| 6 | 6 | ||||||||||||||||||
| Sharon Walraven
| 1 | 2 | ||||||||||||||||||
| Sharon Walraven
| 6 | 6 | ||||||||||||||||||
| Jiske Griffioen
| 4 | 2 | ||||||||||||||||||
| Sharon Walraven
| 7 | 5 | 6 | |||||||||||||||||
| Korie Homan
| 61 | 7 | 1 | |||||||||||||||||
| Korie Homan
| 7 | 3 | 6 | |||||||||||||||||
 Florence Gravellier
| 5 | 6 | 3 | |||||||||||||||||