The 2011 Eastern Illinois Panthers football team represented Eastern Illinois University as a member of the Ohio Valley Conference (OVC) during the 2011 NCAA Division I FCS football season. Led by Bob Spoo in his 24th and final year as head coach, the Panthers compiled an overall record of 2–9 with a mark of 1–7 in conference play, placing last out of nine teams in the OVC. Eastern Illinois played home games at O'Brien Field in Charleston, Illinois.
Schedule
| Date | Time | Opponent | Site | TV | Result | Attendance |
|---|
| September 1 | 6:30 pm | Illinois State* | | CSN Chicago | W 33–26 | 9,111 |
| September 10 | 2:30 pm | at Northwestern* | | BTN | L 21–42 | 28,042 |
| September 17 | 6:30 pm | Tennessee Tech | - O'Brien Field
- Charleston, IL
| | L 20–31 | 6,157 |
| September 24 | 6:00 pm | at No. 16 Jacksonville State | | | L 21–28 | 14,813 |
| October 1 | 6:00 pm | at Southeast Missouri State | | | L 30–37 | 7,757 |
| October 8 | 1:30 pm | Eastern Kentucky | - O'Brien Field
- Charleston, IL
| WEIU | L 16–48 | 9,063 |
| October 15 | 3:00 pm | at Murray State | | | L 27–36 | 7,857 |
| October 22 | 1:30 pm | UT Martin | - O'Brien Field
- Charleston, IL
| WEIU | L 23–24 | 6,832 |
| October 29 | 4:00 pm | at Austin Peay | | | W 19–10 | 5,273 |
| November 5 | 1:30 pm | Tennessee State | - O'Brien Field
- Charleston, IL
| WEIU | L 17–18 | 6,774 |
| November 12 | 2:00 pm | at Southern Illinois* | | | L 28–45 | 7,447 |
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References
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National championship seasons in bold |