2022 Serbia Open – Singles

Singles
2022 Serbia Open
Champion	Andrey Rublev
Runner-up	Novak Djokovic
Score	6–2, 6–7(4–7), 6–0
Draw	28 (4 Q / 3 WC )
Seeds	8

Andrey Rublev defeated Novak Djokovic in the final, 6–2, 6–7^(4–7), 6–0 to win the singles tennis title at the 2022 Serbia Open.

Matteo Berrettini was the reigning champion,^[1] but chose not to defend his title.

The top four seeds received a bye into the second round.

	Semifinals							Final
	1	Novak Djokovic	4	6	6
	3	Karen Khachanov	6	1	2
								1	Novak Djokovic	2	77	0
								2	Andrey Rublev	6	64	6
	6	Fabio Fognini	2	2
	2	Andrey Rublev	6	6

	First round							Second round							Quarterfinals							Semifinals
								1	N Djokovic	2	78	77
	WC	H Međedović	4	5					L Đere	6	66	64
		L Đere	6	7											1	N Djokovic	4	6	6
		D Thiem	3	6	4										7	M Kecmanović	6	3	3
		J Millman	6	3	6				J Millman	4	65
		R Gasquet	0	3				7	M Kecmanović	6	77
	7	M Kecmanović	6	6																		1	N Djokovic	4	6	6
																						3	K Khachanov	6	1	2
								3	K Khachanov	w/o
		M Ymer	5	0				Q	R Safiullin
	Q	R Safiullin	7	6											3	K Khachanov	7	6
	Q	T Monteiro	6	6											Q	T Monteiro	5	4
		J Sousa	4	3				Q	T Monteiro	6	6
		D Goffin	3	64				8	F Krajinović	4	1
	8	F Krajinović	6	77

	First round							Second round							Quarterfinals							Semifinals
	6	F Fognini	65	6	6
		M Cecchinato	77	2	2			6	F Fognini	6	6
	WC	M Kukushkin	64	6	3			PR	A Bedene	2	3
	PR	A Bedene	77	4	6										6	F Fognini	7	6
	WC	A Tabilo	0	3												O Otte	5	4
		O Otte	6	6					O Otte	64	6	6
								4	A Karatsev	77	1	3
																						6	F Fognini	2	2
	5	C Garín	3	1																		2	A Rublev	6	6
		H Rune	6	6					H Rune	3	77	3
		D Lajović	6	1	62			Q	T Daniel	6	61	6
	Q	T Daniel	2	6	77										Q	T Daniel	3	3
		H Laaksonen	2	5											2	A Rublev	6	6
	Q	J Lehečka	6	7				Q	J Lehečka	6	61	2
								2	A Rublev	4	77	6

	First round							Qualifying competition
	1	Jiří Lehečka	6	6
		Nino Serdarušić	0	4
								1	Jiří Lehečka	6	77
								7	Flavio Cobolli	4	63
	WC	Nikola Đošić	1	2
	7	Flavio Cobolli	6	6

	First round							Qualifying competition
	2	Taro Daniel	7	6
	Alt	Aleksandr Nedovyesov	5	1
								2	Taro Daniel	6	6
								5	Liam Broady	1	3
	WC	Jakub Menšík	2	1
	5	Liam Broady	6	6

	First round							Qualifying competition
	3	Norbert Gombos	6	6
		Cedrik-Marcel Stebe	4	3
								3	Norbert Gombos	2	77	0
								8	Roman Safiullin	6	62	6
		Max Purcell	77	4	4
	8	Roman Safiullin	63	6	6

	First round							Qualifying competition
	4	Thiago Monteiro	77	4	6
		Giulio Zeppieri	64	6	4
								4	Thiago Monteiro	6	3	6
								6	Damir Džumhur	3	6	4
		Gilles Simon	6	5	2
	6	Damir Džumhur	3	7	6

• Main draw
• Qualifying draw