A22
A22 or A-22 is a three-character acronym that may refer to:
Vehicles
- A 22 (keelboat), a sailing yacht
 - A-22 Maryland, an American light bomber of World War II manufactured by Glenn L. Martin Company
 - Aero A.22, a Czech civil utility aircraft built during the 1920s
 - Aeroprakt A-22, a Ukrainian ultralight aircraft
 - Arrows A22, a Formula One car
 - Fiat A.22, a piston aero-engine used on the 1925 Italian aircraft Ansaldo A.120
 - IVL A.22 Hansa, a 1922 Finnish license copy of the German two-seat, low winged single-engined seaplane Hansa-Brandenburg W.33
 - MAN A22, internal code for the NLxx3F low-floor single-deck bus chassis built by MAN
 
Biomedicine
- British NVC community A22 (Littorella uniflora - Lobelia dortmanna community), a plant community
 - ICD-10 code for Anthrax
 - Chemical compound A22 (S-[3,4-dichlorobenzyl] isothiourea hydrochloride) with antibiotic activity
 
Others
- A22 Sports Management, company aiming to create a European Super League in association football
 - List of A22 roads
 - English Opening, Encyclopaedia of Chess Openings code