Big Muddy
Big Muddy may refer to:
Places
- Big Muddy, Wyoming, U.S.
 - Big Muddy Badlands, Saskatchewan, Canada, and Montana, U.S.
 
Waterways
- Big Muddy Creek (Missouri River tributary), Saskatchewan, Canada, and Montana, U.S.
 - Big Muddy Creek (East Fork Grand River tributary), a stream in Missouri
 - Big Muddy Creek (Grand River tributary), a stream in Missouri
 - Missouri River, nicknamed "Big Muddy"
 - Mississippi River, nicknamed "The Big Muddy"
 - Big Muddy River, Illinois, U.S.
 - Big Muddy Creek (New Zealand), near the Upper Nihotupu Reservoir
 - Big Muddy Lake, a lake in Saskatchewan
 
Other uses
- Big Muddy (film), a 2015 Canadian crime drama
 - Big Muddy National Fish and Wildlife Refuge, along the Missouri River, U.S.
 - Big Muddy oil field, Wyoming, U.S.
 - Big Muddy Records, an independent American music record label
 - Big Muddy River Correctional Center, in Ina, Jefferson County, Illinois
 - Weyburn-Big Muddy, an electoral district in Saskatchewan, Canada
 - "Big Muddy", a song by Bruce Springsteen from the 1992 album Lucky Town
 
See also
- "Waist Deep in the Big Muddy", a 1967 anti-war song by Pete Seeger