Crotogoudin

Crotogoudin
Names
Other names
(+)-Crotogoudin
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
UNII
  • InChI=1S/C20H26O3/c1-12(2)15-6-10-19-9-5-14(13(3)17(19)22)11-20(19)18(15,4)8-7-16(21)23-20/h14-15H,1,3,5-11H2,2,4H3/t14-,15+,18+,19+,20+/m1/s1
    Key: HXJHRPFDRBBYKZ-KRUJCJHPSA-N
  • CC(=C)[C@@H]1CC[C@]23CC[C@H](C[C@]24[C@]1(CCC(=O)O4)C)C(=C)C3=O
Properties
C20H26O3
Molar mass 314.425 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references

Crotogoudin is a cytotoxic diterpene compound derived from the Madagascan croton plant from which crotobarin was similarly isolated. In in vitro studies, it showed antiproliferative activity against various human cancer cell lines.[1]

References

  1. ^ Breitler, Simon; Carreira, Erick M. (2013). "Total Synthesis of (+)-Crotogoudin". Angewandte Chemie International Edition. 52 (42): 11168–11171. doi:10.1002/anie.201305822. ISSN 1433-7851. PMID 24039092.


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