Edward Thomas O'Brien (September 12, 1914 – September 15, 1976) was an American runner who competed mainly in the 400 meters.  He competed for the United States in the 1936 Summer Olympics held in Berlin, Germany, in the 4 × 400 meter relay, where he won the silver medal with his teammates Harold Cagle, Robert Young and Alfred Fitch.
O'Brien was All-American in the 400 meters three years in a row. He graduated from Syracuse University in 1937, and was inducted into the Syracuse Hall of Fame, with his trophies on display there. He married Florence Quintin in 1937. He enlisted in the United States Navy in December 1941, serving on a destroyer in the South Pacific.
He had one child, Edward T. O'Brien Jr., a psychologist who resides in Clearwater, Florida. O'Brien died on September 15, 1976, of colon cancer after living for several years at his home in Bermuda.
References
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| 1876-1979 Amateur Athletic Union
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| 1980-1992 The Athletics Congress
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| 1992 onwards USA Track & Field
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| Notes | 
Note 1: In 1888 both the NAAAA and the AAU held championships
 OT: The 1920, 1928, 1932, and since 1992, championships incorporated the Olympic Trials, otherwise held as a discrete event.
 2020 OT: The 2020 Olympic Trials were delayed and held in 2021 due to the COVID-19 pandemic.
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| 1906–1979 Amateur Athletic Union
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1906: Eli Parsons1907: Eli Parsons1908: Mel Sheppard1909: Mel Sheppard1910: Harry Gissing1911: Abel Kiviat1913: Abel Kiviat1914: Thomas Halpin1915: Thomas Halpin1916: William Bingham1917: Earl Eby1918: Marvin Gustavson1919: Jack Sellers1920: Earl Eby1921: Fred Murrey1922: Sid Leslie1923: Earl Eby1924: Walter Mulvihill1925: Vincent Lally1926: Horatio Fitch1927: George Leness1928: .svg.png) Phil Edwards (BGU), George Leness (2nd)1929: .svg.png) Phil Edwards (BGU), Eddie Blake (2nd)1930: .svg.png) Phil Edwards (BGU), Eddie Roll (2nd)1931: .svg.png) Phil Edwards (BGU), Eddie Blake (4th)1932: .svg.png) Alex Wilson (CAN), Edwin Roll (2nd)1933: Milton Sandler1934: Milton Sandler1935: Milton Sandler1936: 1937: 1938: Jim Herbert1939: Charles Beetham1940: Charles Belcher1941: Jim Herbert1942: Roy Cochran1943: Lewis Smith1944: Bob Ufer1945: Elmore Harris1946: Elmore Harris1947: George Guida1948: Dave Bolen1949: Dave Bolen1950: Hugo Maiocco1951: Hugo Maiocco1952: Charles Moore1953: Mal Whitfield1954: Reggie Pearman1955: Charles Jenkins Sr.1956: Lou Jones1957: Charles Jenkins Sr.1958: Charles Jenkins Sr.1959: Josh Culbreath1960: Tom Murphy1961: Eddie Southern1962: .svg.png) Bill Crothers (CAN), Jack Yerman (2nd)1963: Jack Yerman1964: Charles Buchta1965: Jack Yerman1966: Theron Lewis1967: Jim Kemp1968: Martin McGrady1969: Martin McGrady1970: Martin McGrady1971:  Andrzej Badeński (POL), Tom Ulan (3rd)1972: Lee Evans1973: Fred Newhouse1974: Wes Williams1975: Wes Williams1976: .svg.png) Fred Sowerby (ANT), Stan Vinson (2nd)1977: .svg.png) Fred Sowerby (ANT), Kevin Prince (2nd)1978: Stan Vinson1979:  Mike Solomon (TRI), Stanley Vincent (3rd)
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| 1980–1992 The Athletics Congress
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| 1993–present USA Track & Field
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| Notes | *Distances have varied as follows: 600 yards (1906–1986), 500 meters (1987–1993) except 600 meters (odd numbered years since 2015) | 
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| Men's track and road athletes
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