Guaifenesin/codeine

Guaifenesin/codeine
Combination of
GuaifenesinExpectorant
CodeineAntitussive
Clinical data
AHFS/Drugs.com
License data
Routes of
administration		By mouth
ATC code
Legal status
Legal status
Identifiers
KEGG

Guaifenesin/codeine is a fixed-dose combination cold medicine used for the treatment of cough.[1] It contains guaifenesin, an expectorant; and codeine, as the phosphate, an opioid antitussive.[1] It is taken by mouth.[1]

It was approved for medical use in the United States in 2006.[1] In 2023, it was the 265th most commonly prescribed medication in the United States, with more than 900,000 prescriptions.[3][4]

Society and culture

Brand names

Guaifenesin/codeine is available under multiple brand names including Allfen CD, Antituss AC, Bitex, Bron-Tuss, Brontex, Cheracol with Codeine, Cheratussin, Cheratussin AC, Codafen, Codar GF, Coditussin AC, Dex-Tuss, Diabetic Tussin C, Duraganidin NR, ExeClear-C, G Tussin AC, Gani-Tuss NR, Glydeine, Guaiatussin AC, Guaiatussin AC Sugar Free, Guaifen AC, Guaifenesin AC, Guiatuss AC, Guiatussin with Codeine, Halotussin AC, Iophen, Iophen-C NR, M-Clear, M-Clear WC, Mar-cof CG, Maxi-Tuss AC, Mytussin AC, Relcof C, Robafen AC, Robichem AC, Robitussin AC, Romilar AC, Tussi Organidin, Tussiden C, Tusso-C, Virtussin A/C, and Virtussin AC.[5][6][7][8]

References

  1. ^ a b c d e "Guaifenesin and codeine phosphate solution". DailyMed. 1 December 2019. Retrieved 19 January 2024.
  2. ^ "Over-the-Counter (OTC) Monograph M012: Cold, Cough, Allergy, Bronchodilator, and Antiasthmatic Drug Products for Over-the-Counter Human Use" (PDF). U.S. Food and Drug Administration (FDA). 14 October 2022. Retrieved 19 January 2024.
  3. ^ "The Top 300 of 2023". ClinCalc. Archived from the original on 17 August 2025. Retrieved 17 August 2025.
  4. ^ "Codeine; Guaifenesin Drug Usage Statistics, United States, 2014 - 2023". ClinCalc. Retrieved 17 August 2025.
  5. ^ "Guaifenesin and Codeine: Indications, Side Effects, Warnings". Drugs.com. 28 July 2023. Retrieved 19 January 2024.
  6. ^ "Codeine and guaifenesin Uses, Side Effects & Warnings". Drugs.com. 16 October 2023. Retrieved 19 January 2024.
  7. ^ "Guaifenesin: MedlinePlus Drug Information". MedlinePlus. Retrieved 19 January 2024.
  8. ^ "Codeine: MedlinePlus Drug Information". MedlinePlus. Retrieved 19 January 2024.


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