Human rhinovirus internal cis-acting regulatory element
| Human rhinovirus internal cis-acting regulatory element (CRE) | |
|---|---|
 Predicted secondary structure and sequence conservation of Rhino_CRE | |
| Identifiers | |
| Symbol | Rhino_CRE |
| Rfam | RF00220 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Viruses |
| SO | SO:0000233 |
| PDB structures | PDBe |
Human rhinovirus internal cis-acting regulatory element (CRE) is a CRE from the human rhinoviruses. The CRE is located within the genome segment encoding the capsid proteins so is found in a protein coding region. The element is essential for efficient viral replication and it has been suggested that the CRE is required for initiation of minus-strand RNA synthesis.[1]
See also
- Human parechovirus 1 (HPeV1) cis regulatory element (CRE)
- Rotavirus cis-acting replication element (CRE)
References
- ^ McKnight KL, Lemon SM (December 1998). "The rhinovirus type 14 genome contains an internally located RNA structure that is required for viral replication". RNA. 4 (12): 1569–1584. doi:10.1017/S1355838298981006. PMC 1369726. PMID 9848654.