ISB
ISB may refer to:
Education
- International School of Brno, Brno, Czech Republic
 - Indian School of Business, Hyderabad, Telangana, India
 - International School of Business (Vietnam) Ho Chi Minh City, Vietnam
 - International School Bangkok, Nonthaburi, Thailand, formerly in Bangkok
 - International School Basel, Basel, Switzerland
 - International School of Beaverton, Aloha, Oregon, United States
 - International School of Beijing, Beijing, China
 - International School of Belgrade, Belgrade, Serbia
 - International School Benghazi, Benghazi, Libya
 - International School of Bergen, Bergen, Norway
 - International School of Boston, Cambridge, Massachusetts, United States
 - International School of Broward, Hollywood, Florida, United States
 - International School Brunei, Bandar Seri Begawan, Brunei
 - International School of Brussels, Brussels, Belgium
 - International School of Bucharest, Bucharest, Romania
 - Instituto Simón Bolívar (Various countries)
 
Music
- I Shalt Become, an American black metal duo
 - The Incredible String Band, a British folk rock musical group of the late 1960s
 - International Society of Bassists, an international society dedicated to the double bass
 - International Staff Band, a brass band of the Salvation Army
 - International Submarine Band, American country-rock group
 
Religion
- Islamic Society of Baltimore, Catonsville, Maryland, United States
 - Islamic Society of Boston, Boston, Massachusetts, United States
 - Islamic Society of Britain, an Islamic organization
 
Science
- International Society for Biocuration
 - International Society of Biomechanics (Various countries)
 - Institute for Systems Biology, non-profit research institute in Seattle, WA
 
Other uses
- Impact Statement for Business, in UK law
 - Imperial Security Bureau, the secret police force of the Empire in the Star Wars universe
 - ISB Engine/Interact System B, a variant of the Cummins B Series engine used in Dodge trucks
 - Independent sideband, radio modulation mode used in some AM radio transmissions
 - International Socialist Bureau, the permanent organization of the Second International
 - Internal Security Bureau, the "TSC police"
 - National Park Service Investigative Services Branch
 - Islamabad International Airport, the current airport of Islamabad and Rawalpindi, Pakistan (IATA airport code: ISB)
- Benazir Bhutto International Airport, formerly Islamabad International Airport, the former airport of Islamabad and Rawalpindi, Pakistan (formerly IATA airport code: ISB)