Iopromide

Iopromide
Clinical data
Trade names	Ultravist
AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy; category	AU: B2; ;
Routes of; administration	Intravascular
ATC code	V08AB05 (WHO) ;
Legal status
Legal status	US: ℞-only;
Pharmacokinetic data
Protein binding	~1%
Metabolism	None
Elimination half-life	2 hours
Excretion	Kidneys
Identifiers
	IUPAC name 1-N,3-N-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-(2-methoxyacetamido)-1-N-methylbenzene-1,3-dicarboxamide;
CAS Number	73334-07-3 ;
PubChem CID	3736;
DrugBank	DB09156 ;
ChemSpider	3605 ;
UNII	712BAC33MZ;
KEGG	D01893 ;
ChEBI	CHEBI:63578 ;
ChEMBL	ChEMBL1725 ;
CompTox Dashboard (EPA)	DTXSID0023163 ;
ECHA InfoCard	100.070.330
Chemical and physical data
Formula	C18H24I3N3O8
Molar mass	791.116 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES CN(CC(CO)O)C(=O)c1c(c(c(c(c1I)NC(=O)COC)I)C(=O)NCC(CO)O)I;
	InChI InChI=1S/C18H24I3N3O8/c1-24(4-9(28)6-26)18(31)12-13(19)11(17(30)22-3-8(27)5-25)14(20)16(15(12)21)23-10(29)7-32-2/h8-9,25-28H,3-7H2,1-2H3,(H,22,30)(H,23,29) ; Key:DGAIEPBNLOQYER-UHFFFAOYSA-N ;
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Iopromide is an iodinated contrast medium for X-ray imaging. It is marketed under the name Ultravist which is produced by Bayer Healthcare. It is a low osmolar, non-ionic contrast agent for intravascular use; i.e., it is injected into blood vessels.^[1]

It is commonly used in radiographic studies such as intravenous urograms, brain computer tomography (CT)^[1] and CT pulmonary angiograms (CTPAs).

Medical uses

The radiocontrast agent is given intravenously in computed tomography (CT) scans, angiography and excretory urography.^[2]

Contraindications

Iopromide use is contraindicated in myelography, cerebral ventriculography and cisternography procedures. It is also contraindicated in those with hyperthyroidism, or with known allergy to the drug.^[3]

Iopromide is also contraindicated in children with prolonged fasting, fluid restriction, on laxative, or dehydration as it can cause renal failure.^[3]

References

^ ^a ^b Haberfeld H, ed. (2020). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Ultravist 300 mg J/ml-Infusionsflaschen.
^ "Prescribing information - Ultravist" (PDF). Bayer Healthcare pharmaceuticals. Archived from the original (PDF) on 10 April 2021.
^ ^a ^b "PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION ULTRAVIST® Iopromide Injection" (PDF). Bayer Healthcare Pharmaceuticals. Archived from the original (PDF) on 27 October 2021. Retrieved 16 April 2024.

External links

Bayer US Ultravist Website

[AC-1] Haberfeld H, ed. (2020). Austria-Codex (in German). Vienna: Österreichischer Apothekerverlag. Ultravist 300 mg J/ml-Infusionsflaschen.

[FDA-2] "Prescribing information - Ultravist" (PDF). Bayer Healthcare pharmaceuticals. Archived from the original (PDF) on 10 April 2021.

[product_monograph-3] "PRODUCT MONOGRAPH INCLUDING PATIENT MEDICATION INFORMATION ULTRAVIST® Iopromide Injection" (PDF). Bayer Healthcare Pharmaceuticals. Archived from the original (PDF) on 27 October 2021. Retrieved 16 April 2024.

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