John Creighton
John Creighton may refer to:
- John Oliver Creighton (born 1943), American astronaut
 - John W. Creighton Jr. (born 1933), American businessman
 - John Creighton, 1st Earl Erne (1731–1828), Irish peer
 - John Creighton (British Army officer) (1772–1833), son of the preceding, MP for Lifford
 - John Creighton, American naval officer involved in the Little Belt affair in 1811
 - John Creighton (archaeologist), British archaeologist
 - John Creighton (judge) (1721–1807), lawyer and judge in Nova Scotia
 - John Creighton (warden) (1817–1885), merchant, politician and prison official in Ontario, Canada
 - John Creighton (Nova Scotia politician) (1794–1878), lawyer and politician in Nova Scotia, Canada
 - John A. Creighton (1831–1907), businessman in Omaha, Nebraska
 - John Creighton (rugby union) (born 1937), New Zealand rugby union player
 - John Creighton (surgeon) (1768–1827), president of the Royal College of Surgeons in Ireland
 - John Creighton (priest) (fl. 1643–1670), Chancellor of Christ Church Cathedral and Dean of Ferns