LSO
LSO may refer to:
Computing
- Large segment offload, a technology for reducing CPU overhead
 - Local shared object, an HTTP cookie-like data entity used by Adobe Flash Player
 - Location search optimization, a web optimization method
 
Organisations
- LSO (company), a delivery company formerly known as Lonestar Overnight
 - Law Society of Ontario, the regulatory body for lawyers in Ontario, Canada (formerly called the Law Society of Upper Canada)
 - Limburg Symphony Orchestra or Limburgs Symfonie Orkest, a Dutch orchestra
 - London School of Osteopathy, an osteopathic school in London, England
 - London Symphony Orchestra, a United Kingdom symphony orchestra
 
Other uses
- Landing signal officer or landing safety officer on an aircraft carrier
 - Lateral superior olive, an auditory nucleus in the brainstem
 - Lutetium orthosilicate, an inorganic scintillator
 - Landing Signal Officer, a naval aviator
 - Lesotho (ISO 3166-1 code)
 - Linguistic Sign-Off