List of highways numbered 253

Route 253 or Highway 253 may refer to:

• Nova Scotia Route 253
• Quebec Route 253

• National Route 253

• Japan National Route 253

• Gochang–Damyang Expressway

• A253 road
• B253 road

• Alabama State Route 253
• Arkansas Highway 253
• California State Route 253
• Georgia State Route 253
• Iowa Highway 253 (former)
• K-253 (Kansas highway)
• Kentucky Route 253
• Maryland Route 253
• Minnesota State Highway 253
• Montana Secondary Highway 253
• New Mexico State Road 253
• New York State Route 253
• Ohio State Route 253
• Pennsylvania Route 253
• South Carolina Highway 253
• South Dakota Highway 253
• Tennessee State Route 253
• Texas State Highway 253 (former)
  • Farm to Market Road 253 (Texas)
• Utah State Route 253 (former)
• Vermont Route 253
• Virginia State Route 253
• Wisconsin Highway 253
• Wyoming Highway 253

Territories

• Puerto Rico Highway 253