The lysophosphatidic acid receptors (LPARs) are a group of G protein-coupled receptors for lysophosphatidic acid (LPA) that include:
See also
References
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| Extracellular | | Eicosanoids |  | 
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 | Lysophospholipids |  | 
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 | Steroids |  | 
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 | Others |  | 
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| Intracellular | | Nuclear receptor |  | 
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 | Second messenger | 
- General: Arachidonic acid
 
- DAG (PKC, TRPC)
 
- IP3 (IP3R, RyR)
 
- Phosphatidic acid
 
- Phosphoinositides: PIP2 (IRKs)
 
- PIP3 (PKB/Akt, Btk, PDPK1)
 
- PtdIns(3,4)P2 (PKB/Akt, PDPK1); Sphingolipids: C1P
 
- Ceramide (CAPPs, KSR1, PKCζ, CTSD)
 
- Glucosylceramides
 
- S1P
 
- Sphingosine (SDK1, PKH, YPK)
  
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| Precursors |  | 
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Receptor (ligands) | | Tooltip Lysophosphatidic acid receptor | 
- Agonists: 1-Oleoyl-LPA
 
- 1-Palmitoyl-LPA
 
- GRI-977143
 
- LPA
 
- OMPT
  
- Antagonists: H2L-5186303
 
- H2L-5765834
 
- Ki-16425
 
- TC-LPA5 4
 
- VPC-32183
  
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 | S1PRTooltip Sphingosine-1-phosphate receptor | 
- Agonists: Amiselimod
 
- Cenerimod
 
- Ceralifimod
 
- CS-2100
 
- CYM-5442
 
- CYM-5520
 
- CYM 5541
 
- CYM-50260
 
- CYM-50308
 
- Dihydro-S1P (sphinganine 1-phosphate)
 
- Fingolimod
 
- Fingolimod phosphate
 
- KRP-203
 
- Mocravimod
 
- Ozanimod
 
- Phyto-S1P
 
- Ponesimod
 
- RP-001
 
- RP-002
 
- RPC-1063
 
- SEW-2871
 
- Siponimod
 
- S1P
 
- SPC
 
- TC-G 1006
 
- TC-SP 14
 
- W-061
 
- XAX-162
  
- Antagonists: CS-0777
 
- CYM-50358
 
- JTE-013
 
- TY-52156
 
- VPC-23019
 
- W-146
  
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Enzyme (inhibitors) |  | 
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| Others |  | 
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See also: Receptor/signaling modulators  |