Portal:Music/DateOfBirth/February 21
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- David Geffen, American record label executive who founded the Asylum Records and Geffen Records imprints, turns 82.
 - Paul Newton, Brit bassist of Uriah Heep fame, turns 80.
 - Christian Vander, French drummer and creator of concept band Magma, turns 77.
 - Jerry Harrison, American guitarist and keyboardist for Talking Heads, turns 76.
 - Jean-Jacques Burnel, Anglo-french bassist and vocalist with The Stranglers, turns 73.
 - Mike Pickering, Brit disc jockey for M People, turns 71.
 - Mary Chapin Carpenter, American singer-songwriter and multiple Grammy Award winner, turns 67.
 - Michael Ward, American guitarist with The Wallflowers, turns 58.
 - James Dean Bradfield, Brit guitarist and vocalist for Manic Street Preachers, turns 56.
 - Charlotte Church, Welsh classical music singer, turns 39.
 - Rhiannon Giddens , American singer-songwriter and musician, turns 48.
 
- Vince Welnick (February 21, 1951 –June 02, 2006), American session musician (keyboards) with The Tubes and Grateful Dead, would have turned 74 this year.
 - Nina Simone (February 21, 1933 –April 21, 2003), American jazz singer, songwriter, pianist, and civil rights activist, would have turned 92 this year.