RCS-8

RCS-8
Legal status
Legal status	CA: Schedule II; DE: NpSG (Industrial and scientific use only); UK: Class B; US: Schedule I;
Identifiers
	IUPAC name 2-(2-Methoxyphenyl)-1-[1-(2-cyclohexylethyl)indol-3-yl]ethanone;
CAS Number	1345970-42-4 [SciFinder];
ChemSpider	24751863 ;
UNII	11030I5W3R;
CompTox Dashboard (EPA)	DTXSID30158821 ;
Chemical and physical data
Formula	C25H29NO2
Molar mass	375.512 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES COc1ccccc1CC(=O)c2cn(c3c2cccc3)CCC4CCCCC4;
	InChI InChI=1S/C25H29NO2/c1-28-25-14-8-5-11-20(25)17-24(27)22-18-26(23-13-7-6-12-21(22)23)16-15-19-9-3-2-4-10-19/h5-8,11-14,18-19H,2-4,9-10,15-17H2,1H3 ; Key:BSQFBMXCQIKYNI-UHFFFAOYSA-N ;
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RCS-8 (also known as 1-(2-cyclohexylethyl)-3-(2-methoxyphenylacetyl)indole, SR-18, and BTM-8) is a synthetic cannabinoid that has been found as an ingredient of "herbal smoking blends". It can be described as an analogue of JWH-250 with the 1-pentyl group replaced by 1-(2-cyclohexylethyl), and can be expected to be less potent than JWH-250.^[1] All CB₁ receptor agonists of the 3-phenylacetylindole class such as RCS-8 are Schedule I Controlled Substances within the United States.^[2]

References

^ Huffman JW, Dai D, Martin BR, Compton DR (1994). "Design, Synthesis and Pharmacology of Cannabimimetic Indoles". Bioorganic & Medicinal Chemistry Letters. 4 (4): 563–566. doi:10.1016/S0960-894X(01)80155-4.
^ 21 U.S.C. § 812: Schedules of controlled substances

[1] Huffman JW, Dai D, Martin BR, Compton DR (1994). "Design, Synthesis and Pharmacology of Cannabimimetic Indoles". Bioorganic & Medicinal Chemistry Letters. 4 (4): 563–566. doi:10.1016/S0960-894X(01)80155-4.

[2] 21 U.S.C. § 812: Schedules of controlled substances

[1]

[2]

See also

References