SANA (drug)

SANA (drug)
Identifiers
  • 2-hydroxy-5-(2-nitroethenyl)benzoic acid
CAS Number
PubChem CID
Chemical and physical data
FormulaC9H7NO5
Molar mass209.157 g·mol−1
3D model (JSmol)
  • C1=CC(=C(C=C1C=C[N+](=O)[O-])C(=O)O)O
  • InChI=1S/C9H7NO5/c11-8-2-1-6(3-4-10(14)15)5-7(8)9(12)13/h1-5,11H,(H,12,13)
  • Key:NVWQBWPWSNPTBM-UHFFFAOYSA-N

SANA (MVD1) is an experimental drug with thermogenic effects which has been researched as a potential weight loss medication.[1][2][3][4]

References

  1. ^ "Eolo Pharma Publishes First-in-Human Study in Nature Metabolism on Novel Obesity Drug Activating Energy-Burning Pathway". eolo-pharma.com.
  2. ^ "In search of an obesity drug: the story of the latin american company Eolo Pharma". CITES - Centro de Innovación Tecnológica, Empresarial y Social. 14 August 2024.
  3. ^ Cal K, Leyva A, Rodríguez-Duarte J, Ruiz S, Santos L, Colella L, et al. (July 2023). "A nitroalkene derivative of salicylate alleviates diet-induced obesity by activating creatine metabolism and non-shivering thermogenesis". Research Square. doi:10.21203/rs.3.rs-3101395/v1. PMC 10371099. PMID 37502859.
  4. ^ Cal K, Leyva A, Rodríguez-Duarte J et al. A nitroalkene derivative of salicylate, SANA, induces creatine-dependent thermogenesis and promotes weight loss. Nat Metab (2025). doi:10.1038/s42255-025-01311-z
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