Samalizumab
| Monoclonal antibody | |
|---|---|
| Type | Whole antibody |
| Source | Humanized (from mouse) |
| Target | CD200 |
| Clinical data | |
| ATC code |
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| Identifiers | |
| CAS Number | |
| ChemSpider |
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| UNII | |
| KEGG | |
| Chemical and physical data | |
| Formula | C6542H10086N1702O2102S46 |
| Molar mass | 147687.22 g·mol−1 |
  (what is this?) (verify) | |
Samalizumab is a humanized monoclonal antibody designed for oncology indications.[1] Samalizumab is a recombinant humanized monoclonal antibody that targets the immunoregulatory protein CD200. Results from a Phase I study indicated the drug has potential for use in treating cancers including chronic lymphocytic leukemia. [2]
Samalizumab was developed by Alexion Pharmaceuticals[3].
References
- ^ "Statement On A Nonproprietary Name Adopted By The USAN Council: Samalizumab" (PDF). American Medical Association.
- ^ Mahadevan D, Lanasa MC, Farber C, Pandey M, Whelden M, Faas SJ, et al. (August 2019). "Phase I study of samalizumab in chronic lymphocytic leukemia and multiple myeloma: blockade of the immune checkpoint CD200". Journal for Immunotherapy of Cancer. 7 (1): 227. doi:10.1186/s40425-019-0710-1. hdl:10150/634601. PMC 6708181. PMID 31443741.
- ^ "Samalizumab Overview - Creative Biolabs". www.creativebiolabs.net. Retrieved 2025-08-21.