FUB-JWH-018 |
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| Legal status |
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(1-(4-Fluorobenzyl)-1H-indol-3-yl)(naphthalen-1-yl)methanone
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| CAS Number | |
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| ChemSpider | |
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| UNII | |
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| CompTox Dashboard (EPA) | |
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| Formula | C26H18FNO |
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| Molar mass | 379.434 g·mol−1 |
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| 3D model (JSmol) | |
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O=C(C1=CC=CC2=C1C=CC=C2)C3=CN(CC4=CC=C(F)C=C4)C5=CC=CC=C53
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InChI=1S/C26H18FNO/c27-20-14-12-18(13-15-20)16-28-17-24(22-9-3-4-11-25(22)28)26(29)23-10-5-7-19-6-1-2-8-21(19)23/h1-15,17H,16H2 Key:VREQTLWJHFQLEX-UHFFFAOYSA-N
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FUB-JWH-018 (also known as FUB-018) is a naphthoylindole-based synthetic cannabinoid, representing a molecular hybrid of JWH-018 and AB-FUBICA or ADB-FUBICA.[1][2]
Legal status
In the United States, all CB1 receptor agonists of the 3-(1-naphthoyl)indole class such as FUB-JWH-018 are Schedule I Controlled Substances.[3]
As of October 2015 FUB-JWH-018 is a controlled substance in China.[4]
See also
References
- ^ "FUB-JWH 018". Cayman Chemical. Retrieved 8 July 2015.
- ^ Lamoureux C (June 2015). "Apport d'un spectromètre UHPLC-HR-Q-TOF pour l'identification des nouvelles substances psychoactives en circulation". Toxicologie Analytique et Clinique. 27 (2): S67. doi:10.1016/j.toxac.2015.03.107.
- ^ 21 U.S.C. § 812: Schedules of controlled substances
- ^ "关于印发《非药用类麻醉药品和精神药品列管办法》的通知" (in Chinese). China Food and Drug Administration. 27 September 2015. Archived from the original on 1 October 2015. Retrieved 1 October 2015.
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Synthetic cannabinoid receptor agonists / neocannabinoids | Classical cannabinoids (dibenzopyrans) | |
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Non-classical cannabinoids | |
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Indazole-3- carboxamides | |
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| Indole-3-carboxamides | |
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| Indole-3-carboxylates | |
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| Naphthoylindazoles | |
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| Naphthoylindoles | |
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| Naphthoylpyrroles | |
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| Naphthylmethylindenes | |
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| Naphthylmethylindoles | |
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| Phenylacetylindoles | |
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| Pyrazolecarboxamides | |
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Tetramethylcyclo- propanoylindazoles | |
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Tetramethylcyclo- propanoylindoles | |
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| Allosteric CBRTooltip Cannabinoid receptor ligands | |
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Endocannabinoid enhancers (inactivation inhibitors) | |
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Anticannabinoids (antagonists/inverse agonists/antibodies) | |
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Receptor (ligands) | | CB1Tooltip Cannabinoid receptor type 1 | Agonists (abridged, full list) | |
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| Inverse agonists | |
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| Antagonists | |
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| CB2Tooltip Cannabinoid receptor type 2 | | Agonists |
- 2-AG
- 2-AGE (noladin ether)
- 3,3'-Diindolylmethane
- 4-O-Methylhonokiol
- α-Amyrin · β-Amyrin
- A-796,260
- A-834,735
- A-836,339
- AM-1172
- AM-1221
- AM-1235
- AM-1241
- AM-2232
- Anandamide
- AZ-11713908
- Cannabinol
- Caryophyllene
- CB-13
- CBS-0550
- CP 55,940
- GW-405,833 (L-768,242)
- GW-842,166X
- HU-308
- JTE 7-31
- JWH-007
- JWH-015
- JWH-018
- JWH-73
- JWH-133
- L-759,633
- L-759,656
- Lenabasum (anabasum)
- Magnolol
- MDA-19
- Nabitan
- NADA
- Olorinab (APD-371)
- PF-03550096
- S-444,823
- SER-601
- Serinolamide A
- UR-144
- Tedalinab
- THC (dronabinol)
- THCV
- Tetrahydromagnolol
- Virodhamine
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| Antagonists | |
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NAGly (GPR18) | |
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| GPR55 | |
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| GPR119 | |
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Transporter (modulators) | | eCBTsTooltip Endocannabinoid transporter | |
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Enzyme (modulators) | | FAAHTooltip Fatty acid amide hydrolase | |
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| MAGL | |
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| ABHD6 |
- Inhibitors: JZP-169
- JZP-430
- KT182
- KT185
- KT195
- KT203
- LEI-106
- ML294
- ML295
- ML296
- UCM710
- WWL-70
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| ABHD12 | |
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| Others |
- Others: 2-PG (directly potentiates activity of 2-AG at CB1 receptor)
- ARN-272 (FAAH-like anandamide transporter inhibitor)
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- See also
- Receptor/signaling modulators
- Cannabinoids (cannabinoids by structure)
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