Alfadolone

Alfadolone
Clinical data
Other names3α,21-dihydroxy-5α-pregnane-11,20-dione
Routes of
administration		Intravenous
ATC code
  • none
Identifiers
  • (3R,5S,9S,14S)-3-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-1,2,3,4,5,6,7,8,9,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-11-one
CAS Number
PubChem CID
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.034.496
Chemical and physical data
FormulaC21H32O4
Molar mass348.483 g·mol−1
3D model (JSmol)
  • O=C2[C@H]3[C@H]([C@@H]1CC[C@H](C(=O)CO)[C@@]1(C)C2)CC[C@H]4C[C@H](O)CC[C@]34C
  • InChI=1S/C21H32O4/c1-20-8-7-13(23)9-12(20)3-4-14-15-5-6-16(18(25)11-22)21(15,2)10-17(24)19(14)20/h12-16,19,22-23H,3-11H2,1-2H3/t12-,13+,14-,15-,16+,19+,20-,21-/m0/s1 checkY
  • Key:XWYBFXIUISNTQG-VKMGZQQJSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Alfadolone (INN), or alphadolone is a neuroactive steroid and general anesthetic.[1] Along with alfaxolone, as alfadolone acetate, it is one of the components of the anesthetic drug mixture althesin.[1]

Chemistry

See also: List of neurosteroids

See also

References

  1. ^ a b Ganellin CR, Triggle DJ (21 November 1996). Dictionary of Pharmacological Agents. CRC Press. pp. 1094–. ISBN 978-0-412-46630-4.



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